Welcome to the Integrative Neurophysiology Laboratory Website

Mission Statement

To identify the neuromuscular mechanisms of human fatigue and physical disability.

Research

The current research at INPL focuses on developing a clearer understanding of fatigue and disability and the treatments in people with Multiple Sclerosis (MS). We also focus on investigating new therapeutic approaches to neurological diseases.

The current basic laboratory research focuses on the following areas:

  1. Investigating the effects of cannabis use in patients with MS on motor and cognitive functions.
  2. Exploring the positive and negative effects of cannabis on quality of life and disability in neurological diseases (e.g. Parkinson’s disease, Multiple Sclerosis, Dementia).
  3. Clarifying the origins of MS related fatigue.
  4. The use of non-invasive neuroimaging techniques (Positron Emission Tomography, Computed Tomography, Magnetic Resonance Imaging) to examine the CNS–skeletal muscle interaction at a whole-body level.

Lab News

  • We are currently recruiting M.S. students for Spring and Fall 2018. Please contact thorsten.rudroff@colostate.edu
  • Dr. Rudroff was interviewed by Global TV, Canada on Cannabis use in adolescents.
  • Dr. Rudroff was appointed to the faculty of the University of Colorado School of Medicine-Department of Radiology/Nuclear Medicine as Adjoint Assistant Professor.
  • Dr. Rudroff and his team received the 2017 CCTSI CSU Pilot Gant : Transcranial Direct Current Stimulation to Lower Neuropathic Pain in People with Multiple Sclerosis: A Mechanistic PET Study.
  • Another successful Annual Meeting of the ACSM Rocky Mountain Chapter. Felix Proessl received a grant to study "Effects of transcranial direct current stimulation on fatigability in people with multiple sclerosis". This is the 5th consecutive year one of our INPL students has received a grant!
  • Dr. Rudroff and his colleagues from Anschutz Medical Campus, Denver, Drs. Jennifer Kwak (Nuclear Medicine) and Justin Honce (Neuroradiology) received a grant from the Colorado Translational Research Imaging Center (C-TRIC) to investigate "Effects of regular cannabis smoking on resting brain function in people with multiple sclerosis: An observational FDG-PET study".

Names left to right: INP Lab: Nathan Ketelhut, Felix Proessl, Thorsten Rudroff, John Kindred, and Kelly Oberg